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Dolomite Microfluidics is simplifying research into drug encapsulation by offering a complete automated system for polymer micro- and nanoparticle generation. The company’s Drug Encapsulation System provides scientists with a quick, simple and scalable way of encapsulating drug samples, without the need for extensive microfluidics knowhow.
The MicroTAS Video Competition 2017, sponsored by Dolomite Microfluidics and Lab on a Chip, and supported by the Chemical and Biological Microsystems Society, saw first prize awarded to Anu Kaushik and Alex Trick, PhD candidates in the BioMEMS and Single Molecule Dynamics Lab at Johns Hopkins University in Baltimore, Maryland.
Anu explained the idea behind their entertaining and creative video: “A few months before the conference, we realized that we both had an interest in hip-hop and rap, as well as playing around with music-making software. We thought a rap parody explaining our research would be a great way to integrate our work with our love of music. The video describes our research on droplet microfluidics for single-cell analysis and the benefits of using this technique to discretize cells from tissue samples to achieve faster detection, increase signal to noise ratio and analyze cellular heterogeneity.”
The Pioneers of Miniaturization Lectureship 2017, sponsored by Dolomite Microfluidics and Lab on a Chip, has been awarded to Professor Aaron Wheeler in recognition of his contribution to digital microfluidics, a technique which involves manipulation of discrete microfluidic droplets on the surface of an array of electrodes coated with a hydrophobic insulator.
Dolomite Microfluidics is making microencapsulation technology more widely accessible with the Telos® droplet system, designed for high throughput and easy scale up. The modular components provide scientists with excellent process control, and the ability to choose from a range of particle diameters between 10 and 50 µm on a single piece of hardware.
Telos® 2 Reagent Chips from Dolomite Microfluidics have helped San Francisco-based ProLynx LLC to develop a novel drug delivery platform. Jeff Henise, Director of Process Development at ProLynx, explained: “Traditional polymer encapsulation delivery systems rely on diffusion or breakdown of the polymer to release their payload. In contrast, our drug delivery system offers controlled release using self-cleaving linkers to attach the drug to hydrogel microsphere carriers....
Dolomite, a world leader in microfluidics innovation, is celebrating the success of its Fluidic Factory 3D printer in the ‘Processing and Prototyping’ category this year’s R&D 100 Awards. This innovative system – the first commercially available 3D printer for fluidically-sealed devices – offers rapid, straightforward and reliable prototyping of microfluidic components, including chips, manifolds, connectors and other devices. Using cyclic olefin copolymer (COC) makes it easy and affordable to 3D print devices for almost any application.
Researchers at the Lawrence Livermore National Laboratory (LLNL) are using a Dolomite Fluidic Factory to help develop a novel carbon capture technology intended for industrial applications1. Mindy Simon, postdoctoral research associate, explained: “Carbon capture is important for power generation and other heavy industries, reducing the amount of carbon dioxide released into the atmosphere. Here at LLNL, we have developed an innovative microcapsule technology which consists of a highly permeable polymer shell surrounding a CO2-absorbing liquid core. These microcapsules can be loaded into columns which can then be placed into a smoke-stack or other industrial outlet, capturing the CO2 before it is released into the environment.”
This year's MicroTAS Video Competition has been won by Enrica Rollo from EPFL (École polytechnique fédérale de Lausanne) in Switzerland, for her entertaining comparison between cleanrooms and kitchens. The annual competition – run by microfluidics specialist Dolomite and Lab on a Chip, and supported by the Chemical and Biological Microsystems Society – embraces the lighter side of life sciences and chemistry, while giving delegates a chance to win €2,500 worth of Dolomite microfluidics equipment.
Dolomite, a world leader in microfluidics innovation, unveiled its innovative Fluidic Factory at Lab-on-a-Chip & Microfluidics 2016 in Madrid, Spain, on the 15th of March.
Dolomite has developed the Meros High Speed Digital Microscope specifically for microfluidic applications. This high resolution imaging system allows users to conveniently monitor high speed microfluidic events, such as droplet formation, using a built-in stage.
A Dolomite microfluidic system is helping Dr Samar Damiati, Assistant Professor in the Biochemistry Department at King Abdulaziz University in Saudi Arabia, perform drug encapsulation studies.
Dolomite, a world leader in microfluidics innovation, has launched the groundbreaking µEncapsulator 1 System, the only microfluidic product specifically designed to meet the needs of research biologists. This user-friendly, high throughput system offers simple, straightforward encapsulation of single cells, DNA and/or functionalised beads in high precision, identically-sized picolitre droplets.
Dolomite, part of the Blacktrace group of companies, is celebrating a decade of excellence in the design and manufacture of novel, high quality microfluidic products, including individual components such as pumps, chips, connectors, temperature controllers and sensors, software solutions and complete microfluidic systems.
Dolomite, a world leader in microfluidics innovation, has launched the Single Cell RNA-Seq Chip for simple, reliable creation of single cell libraries.
Dolomite, a world leader in microfluidics innovation, will be previewing its innovative Fluidic Factory at MicroTAS 2015 in Gyeongju, Korea, on the 25th of October.
Microfluidics specialist Dolomite has teamed up with Lab on a Chip and the Chemical and Biological Microsystems Society to create the first ever MicroTAS Video Competition.
Dolomite, a pioneering microfluidics specialist, and Lab on a Chip are pleased to announce the winner of the Productizing Science® 2015 competition, Zimmertech AS.
Dolomite Microfluidics, the world leader in innovative microfluidic products, has seen significant growth in the sale of its Micro Droplet Systems, particularly for cell encapsulation applications.
Dolomite, a world leader in microfluidics innovation, has launched new flexible, cost-effective Flow Chemistry Systems at the 250th American Chemical Society Meeting and Exposition in August 2015.
In an article published in the May edition of Speciality Chemicals Magazine, Professor Ardson dos Santos Vainna, Department of Chemical Engineering, São Paulo State University, discusses how the use of a continuous flow chemistry process in a Syrris Asia Flow Chemistry microreactor system enhances the efficiency of styrene polymerization.
We’re excited to announce that Syrris will be exhibiting at the much-anticipated ACHEMA chemistry show in Frankfurt, Germany (11th – 15th June 2018). Syrris’ resident flow chemistry expert, Andrew Mansfield, will be presenting a range of free-to-attend 10-minute lightning talks on various flow chemistry topics. Presented on the Syrris stand in the Flow Chemistry Pavilion, the talks are aimed at helping chemists to better understand the benefits of flow chemistry and the scope of what can be achieved using flow chemistry systems. Read on for a full breakdown of the talks.
In an article published on pharmtech.com, Nicola Tirelli, Professor and Senior Researcher at the Laboratory of Polymers and Biomaterials, Italian Institute of Technology, explains how variation in drug-loaded polymer nanoparticle synthesis is reduced with flow chemistry, compared to traditional batch chemistry techniques.
UK researchers may have saved chemists hours of manually tuning their reactions, thanks to a free and user-friendly computational software tool they’ve developed in which they used a Syrris Asia Flow Chemistry Syringe Pump.
Day 15: Stuart gets by with a little help from his friend - September 27th, 2017
Today’s meeting in Guangzhou Nansha started at 9:20h and was with a pharma company who were looking to understand more about flow chemistry. They’d started researching the subject and were very happy that we could visit them and show them our range of flow chemistry systems. There were about 23 people across different departments in the company: process, safety, analytical and chemists. They bombarded us with questions during the presentations of the systems, which was great! Really showed their interest and enthusiasm.
Syrris’ state-of-the-art Orb batch reactors are designed by chemists for chemists, ensuring they perfectly meet the demands of your work. Whether you are engaged in lab scale reactions or looking to move to pilot scale processes, there is an Orb system designed for you.
Syrris, a world leader in chemistry product innovation, is launching the Orb Pilot jacketed reactor this fall. This unique system, which offers flexible and cost-effective pilot scale batch chemistry, will be unveiled at P-MEC Barcelona from the 4-6 October 2016.
Syrris, a world leader in chemistry process innovation, is previewing its revolutionary Titan system at P-MEC in Barcelona, Spain, from the 4th to the 6th of October. This modular continuous chemical processing system is designed to enable straightforward scale-up, from kilo lab through pilot plant to manufacturing.
Syrris, a world leader in the field of flow chemistry, launched its Asia Automated Reagent Injector at the 252nd American Chemical Society National Meeting and Exposition in Philadelphia, USA. This latest innovation is designed for use with Asia flow chemistry systems, enabling fully automated experiments with multiple reagents.
Syrris – a Blacktrace Holdings brand – is celebrating 15 years of creating pioneering chemistry solutions. Founded in August 2001 to address some of the technology challenges faced by the pharmaceutical industry, the company's focus on improving productivity in R&D chemistry has ensured that it rapidly became a leading provider across various sectors, such as the pharmaceutical manufacturing, petrochemistry, agrochemistry and fine chemical synthesis industries.
Syrris, a world leader in chemistry product innovation, is launching the Atlas HD automated jacketed reactor system at the upcoming American Chemical Society (ACS) National Meeting and Exposition in Philadelphia.
Syrris, a world leader in chemistry product innovation, is previewing its Orb Pilot jacketed reactor at the 252nd American Chemical Society (ACS) National Meeting and Exposition.
Syrris, a world leader in chemistry product innovation, has launched the Titan Syringe Pump, a continuous flow chemical processing module. Suitable for lab, pilot and production scale applications, this extremely chemically-resistant single channel pump combines powerful drive motors, clever valve design and software control to deliver ultra-smooth flow rates from 1 to 250 ml/min.
Syrris, a world leader in the field of flow chemistry, previewed its Asia Automated Reagent Injector at the SCI/RSC Continuous Flow Technology conference in Cambridge, UK, on the 15th of March. This latest innovation is designed for use with Asia flow chemistry systems, enabling fully automated experiments with multiple reagents.
Syrris has updated its revolutionary Asia range of flow chemistry systems, introducing a number of new modules and application-focused solutions. Designed by chemists for chemists, these award-winning systems have been developed to offer exceptional ease of use and enable a wide variety of chemical reactions.
Syrris, a world leader in flow product innovation, has been a driving force in enhancing R&D chemistry productivity ever since the company's foundation 14 years ago. This achievement is amply recognised by the wealth of impressive publications describing novel flow chemistry applications developed using Syrris reactors.
A ChemiSens Calorimeter is helping researchers at Germany’s Max Planck Institute of Colloids and Interfaces to quantitatively evaluate polymerization reaction profiles and accurately determine end points.
Syrris' sister company, Dolomite Microfluidics, has launched new flexible, cost-effective Dolomite Flow Chemistry Systems at the 250th American Chemical Society Meeting and Exposition in August 2015.
Syrris will be launching Orb, a novel jacketed reactor system at the 250th American Chemical Society Meeting and Exposition on the 16th of August 2015. Orb combines exceptional value and high quality construction with unique user-friendly features and reliable performance for batch chemistry.
Explosives manufacturer Eurenco, based in Karlskoga, Sweden, relies on a ChemiSens Calorimeter to ensure the safety of its production processes. Helen Stenmark, R&D manager for explosives and propellants, explained: "Safety is paramount when you are working with explosives. Our reactions involve a great deal of energy, and it is vital to have the right equipment – for cooling and stirring, for example – to safely control the process."
Glass Solutions, a world leader in the manufacture of high quality, precision glassware, is the supplier of choice for a wide variety of laboratories, providing specialist scientific glassware backed by unrivalled service and support. With extensive in-house expertise, combined with the UK’s largest advanced glass-blowing facility, the company is ideally placed to produce exceptional quality, precision manufactured glassware to suit a wide variety of laboratory applications.
Innoval Technology – a global aluminium consultancy company – relies on Glass Solutions to supply precision-manufactured bodies for glass tube brazing furnaces. Adam Nadin, a metallurgical engineer at Innoval, explained: “Many of the companies that manufacture aluminium components do not have in-house laboratories, so rely on our expertise to provide process support and product-related solutions. Using a glass tube brazing furnace, our Materials Testing Team can quickly and accurately simulate industrial conditions on a small scale.”
ALS Food and Pharmaceutical, based in Chatteris, UK, relies on Glass Solutions to maintain its laboratory glassware.
Glass Solutions is the world leader in high quality, precision glassware for scientific, architectural and engineering applications, and offers bespoke design and glass blowing capabilities to match individual customer needs.
Glass Solutions is working with bespoke furniture and lighting designers FRD Ltd to produce individual lighting installations for both private and public spaces.
Bolton-based PTFE Developments Ltd. specialises in the production of fluoropolymer-lined chemical process equipment for the chemical and pharmaceutical industries, relying on Glass Solutions to supply the high quality glass used in its tubular sight glasses.
Glass Solutions, a world leader in the manufacture of high quality, precision glassware, is the supplier of choice for numerous design agencies, architects and production companies requiring custom-designed, decorative pieces of glassware.
Glass Solutions has collaborated with production company Atom Ltd to manufacture a unique high quality glass trophy for a large multinational company.
Glass Solutions hand-blown precision glassware is key to the continued success of Yorkshire-based LabPlant UK's laboratory scale spray dryers.
Haberdashery, a London-based design consultancy, relies on Glass Solutions to produce top quality, custom-made glassware for its landmark sculptural lighting commissions.
Blackpool-based RocketScienceMods, a manufacturer of high-end electronic cigarette components, turned to glassware specialist Glass Solutions to meet its need for a bespoke high quality drip tip.
Glass Solutions has launched a range of jacketed reactor systems combining excellent value with reliable performance for process development, reaction optimization, or production applications.
After spending the summer preparing the new 12000sq ft facility with the very latest infrastructure, Glass Solutions has now relocated both its March and Cambridge sites.
Glass Solutions is delighted to announce its recent acquisition of Labglass Ltd, the reaction vessel specialist based in north Cambridgeshire.
During the summer Glass Solutions had the opportunity to manufacture a series of glass shades for installation into one of London’s top hotels. Like everything else that had been commissioned for this project it was on a grand scale.
It takes more than a good idea to make something truly remarkable, and a product can’t be a company’s only asset; the people are equally, if not more, valuable. At Particle Works, we remain committed to the belief that our true value lies with the people behind the particles, who make it all possible.
Particle Works – the nano- and microparticle materials specialist – has developed a range of high quality quantum dots for use in diagnostic, biomedical and optoelectronic applications.
Particle Works – a Blacktrace Holdings brand – is a world leader in the synthesis of nano- and microparticles.
Particle Works – the nano- and microstructured material specialist – has developed a range of alginate and agarose hydrogel beads designed to enable three dimensional cell culture growth.
Particle Works – the nano- and microstructured material specialist – provides microencapsulation services for drug development applications, including controlled drug release, solubility enhancement or targeted drug delivery.
Blacktrace Holdings Limited, a leading group of companies focused on Productizing Science®, will be launching its latest brand, Particle Works, at the NANOTEXNOLOGY 2016 conference in Thessaloniki, Greece, from the 4th to the 8th of July.
Particle Works, supplier of high-performance micro-and-nanostructured materials, has released a range of metal nanoparticles specifically engineered to achieve high performance in applications such as lateral flow assays, catalysis, photo thermal heating, drug delivery and magnetic separation.
Particle Works, a world leader in the manufacture of high performance particles, offers significant benefits to a wide range of applications. Particle Works supplies micro-and nanostructured for lateral flow assays, bio imaging, catalysts, light emitting materials, magnetic materials, targeted drug delivery, controlled drug release and cell growth medium.
Particle Works is very excited to announce the launch of its website. Particle Works manufactures high performance micro- and nanomaterials for a wide range of applications, and being able to find information about our products and services quickly and easily is crucial for visitors. Customers are at the heart of our website design - we have made sure that the website is easy to use, simple to navigate, visually appealing and that it displays large images of products and key information at a glance with an option to expand.
Dolomite Bio, a brand of Blacktrace Holdings Limited, celebrated the first anniversary of its launch on March 1st, marking the end of a fruitful year in business. This biology-focused brand, a spin out from sister company Dolomite Microfluidics, is dedicated to the development of innovative products for high throughput single cell encapsulation.
Dolomite Bio has launched a new Injection Valve and Sample Loop for single cell RNA sequencing workflows. This option enables straightforward, gentle introduction of evenly distributed mRNA capture beads into the company’s RNA-Seq System for individual encapsulation of cells.
Researchers at The Institute of Cancer Research (ICR), London, are taking advantage of the single cell encapsulation capabilities of Dolomite Bio’s Single Cell RNA-Seq System to investigate resistance mechanisms in prostate cancer. Karolina Nowakowska, a PhD student at The Institute of Cancer Research, explained: “Our team is focused on studying treatment resistance in prostate cancer patients, looking at the biochemical mechanisms responsible.
Dolomite Bio’s Single Cell RNA-Seq System is helping researchers at the University of Helsinki to investigate autoimmune diseases. Focusing on gastrointestinal conditions – such as coeliac disease and inflammatory bowel disease – the Molecular Genetics of Immunological Diseases group is using the system to study T-cell activation and response at the single cell level.
Dolomite Bio has developed the Single Cell RNA-Seq System for efficient, high throughput single cell transcriptomics. This compact, scalable system enables rapid, reproducible droplet encapsulation of individual cells, allowing up to 10,000 single cell libraries to be generated in one 15-minute run.
Blacktrace Holdings Limited, a leading group of companies focused on Productizing Science®, is pleased to announce the launch of its latest brand, Dolomite Bio. This biology-focused brand – spun out from sister company Dolomite Microfluidics – is dedicated to the development of innovative products for high throughput single cell research.
Dolomite Bio has developed the Meros High Speed Digital Microscope specifically for microfluidic applications. This high resolution imaging system allows users to conveniently monitor high speed microfluidic events, such as droplet formation, using a built-in stage.
Dolomite Bio, a world leader in microfluidics innovation, has launched the ground-breaking µEncapsulator 1 System, the only microfluidic product specifically designed to meet the needs of research biologists. This user-friendly, high throughput system offers simple, straightforward encapsulation of single cells, DNA and/or functionalised beads in high precision, identically-sized picolitre droplets.
Dolomite, part of the Blacktrace group of companies, is celebrating a decade of excellence in the design and manufacture of novel, high quality microfluidic products, including individual components such as pumps, chips, connectors, temperature controllers and sensors, software solutions and complete microfluidic systems.
Dolomite, a world leader in microfluidics innovation, has launched the Single Cell RNA-Seq Chip for simple, reliable creation of single cell libraries. This new chip allows researchers to use droplet-based microfluidic methods to help explore the behaviour of thousands of individual cells, providing a rapid and easy way to screen for new or cryptic cell types.
Dolomite Microfluidics, the world leader in innovative microfluidic products, has seen significant growth in the sale of its Micro Droplet Systems, particularly for cell encapsulation applications.
A Dolomite droplet generation system is helping researchers at Weill Cornell Medical College in New York, USA, to encapsulate human and mouse B cells for the cloning of antibody genes.
Microfluidics specialist Dolomite has created a low cost kit aimed at educational initiatives or those new to microfluidics. The Educational Microfluidic Starter Kit offers connect-and-go microfluidic capabilities, allowing easy set-up without the need for specialist tools or a gas supply.
