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Going with the Flow – Syrris launch new FRX systems for flow chemistry

Royston, UK – Syrris have announced the introduction of their new easy to use flow chemistry experimental system called FRX. With the FRX, reactions occur under laminar flow conditions, improving reaction speed, optimisation and control. The FRX flow chemistry systems are modular, allowing chemists to select the system that best meets their individual needs, and can be easily upgraded to meet changing demands, at an affordable price. With a small footprint, the FRX fits effortlessly into the laboratory workspace.

FRX 400 system

4pumpfrx400_200FRX400 part of the FRX™ range of flow chemistry systems The FRX product range is based on work pioneered by Prof Steven Ley of the University of Cambridge and his team. The four FRX systems, 100, 200, 300 & 400, span a range of functionalities and offer simple manual mode operation from the instrument front panel. Systems also allow both a solid and solution phase chemistry to be performed, vastly expanding the range of reaction types that can be carried out in flow. Furthermore, high-pressure capabilities permit the super heating of solvents and further increase reaction speed.

Modularity provides flexibility and easy integration of new units for increased reaction steps or more complex set-ups when required. Both the wide flow range pump and reaction heating systems allow multiple reaction conditions to be run. Additionally, analysis can be undertaken throughout the reaction by manually diverting a small quantity of the reaction product for testing.

The FRX systems range from the more basic 100, designed for initial flow chemistry work using a larger volume tube reactor, and the 200 with a microreactor and solid phase column – to the more complex 300 and 400 for multi-step chemistry and more sophisticated set ups. Both the FRX 300 and 400 incorporate an FRX Flow Liquid-Liquid EXtraction module (FLLEX). The FLLEX facilitates compound purification and separation post reaction, which once separated can be passed for collection, analysis or further reaction. In addition to small scale optimisations, the high end FRX 400 can also allow reaction cooling and be used with solid supported chemistries.

The new FRX systems are the latest additions to further expand Syrris’s impressive portfolio of flow chemistry instrumentation. The Syrris AFRICA system is a highly automated system, and it has become clear that a range of our customers wish to gain access to the benefits of flow chemistry without the level of automation that AFRICA provides. FRX has been developed as that more accessible system. Any chemistry done on FRX can be transferred easily to AFRICA at a later point if the user wishes.

Click here to see the Syrris AFRICA system